Review Article
The Current Concept of T H 17 Cells and Their Expanding Role in Systemic Lupus Erythematosus
Table 1
IL-17 in murine models of lupus.
| Model | Description | References |
| BXD2 | IL-17 promotes spontaneous GC development as well as autoantibody production by IL-17R+ B cells | [82, 83] | MRL.lpr | Expansion of IL-17-producing DNT cells with kidney infiltration and GN induction | [91, 92] | SNF1 | Enhanced IL-17 production by CD4+ T cells with kidney infiltration | [94] | NZM2328 | Disruption of TNFα promotes Th17 development | [97] |
|
|