A Synoviocyte Model for Osteoarthritis and Rheumatoid Arthritis: Response to Ibuprofen, Betamethasone, and Ginger Extract—A Cross-Sectional In Vitro Study

Table 3

Mean and confidence interval for IL-6 production in cells unstimulated and stimulated with TNF-𝛼. Concentrations in pg/mL.

	Diagnose OA	Diagnose RA	Diagnose N
Betamethasone; Not stimulated	25.61; (13.37; 49.02)	16.30; (8.08; 32.86)	19.22; (7.98; 46.32)
Betamethasone; Stimulated	32.04; (16.74; 61.34)	48.36; (23.89; 98.07)	44.94; (18.65; 108.27)
Ibuprofen; Not stimulated	71.13; (37.18; 136.08)	45.27; (22.46; 91.23)	53.40; (22.18; 128.59)
Ibuprofen; Stimulated	89.01; (46.53; 170.29)	134.34; (66.55; 271.22)	124.84; (51.84; 300.61)
Control; Not stimulated	75.98; (39.72; 145.37)	48.36; (23.99; 97.46)	57.05; (23.69; 137.37)
Control; Stimulated	95.09; (49.70; 181.91)	143.5; (71.08; 289.73)	133.36; (55.38; 321.12)
Ginger Extract; Not stimulated	36.05; (18.85; 68.98)	22.94; (11.38; 46.24)	27.07; (11.24; 65.18)
Ginger Extract; Stimulated	45.12; (23.58; 86.32)	68.10; (33.73; 137.48)	63.28; (26.28; 152.37)