Research Article
Autoimmune Thyroid Disease in Rheumatoid Arthritis: A Global Perspective
Table 2
Bivariate analysis of categorical variables.
| Characteristic | RA with AITD | RA without AITD | OR | 95% CI | P |
| MAS | 10/61 (16.39) | 7/650 (1.08) | 18.01 | 6.57–49.30 | <0.0001 | Type 2 Diabetes | 12/72 (16.67) | 20/665 (3.01) | 6.45 | 3.00–13.83 | 0.008 | Methotrexate | 75/78 (96.15) | 627/716 (87.57) | 3.54 | 1.09–11.49 | 0.024 | Female | 72/78 (92.31) | 575/719 (79.97) | 3.01 | 1.2–7.05 | 0.008 | Thrombosis | 9/71 (12.68) | 30/667 (4.50) | 3.01 | 1.4–6.78 | 0.003 | Anti La+ | 6/39 (15.38) | 14/246 (5.69) | 3.01 | 1.08–8.3 | 0.04* | Anti Ro+ | 11/39 (28.21) | 32/248 (12.90) | 2.65 | 1.20–5.84 | 0.013 | Abnormal BMI | 37/69 (53.60) | 250/612 (40.8) | 1.67 | 1.01–2.76 | 0.042 | Low educational level | 15/59 (25.4) | 249/633 (39.3) | 0.52 | 0.28–0.96 | 0.035 | Abnormal cholesterol | 17/43 (39.53) | 162/290 (55.86) | 0.51 | 0.26–0.99 | 0.045 | RF+ | 50/73 (68.49) | 523/644 (81.21) | 0.50 | 0.29–0.85 | 0.01 | Polyautoimmunity | 78/78 (100) | 35/722 (4.8) | N/A | N/A | N/A | TPOAb+ | 51/54 (94.44) | 0/81 (0.00) | N/A | N/A | N/A | TgAb+ | 26/50 (52.00) | 0/75 (0.00) | N/A | N/A | N/A |
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Fisher’s exact test. 95% CI: 95% confidence interval; AITD: autoimmune thyroid disease; BMI: body mass index; N/A: not assessed; OR: odds ratio; RA: rheumatoid arthritis; RF: rheumatoid factor; TgAb: anti-thyroglobulin; TPOAb: anti-thyroperoxidase enzyme.
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