Table 3: Baseline and weeks 6 and 12 changes (LS mean ± SE).

VariableWeek 0 (range)Week 6 changeEffect sizeAdjusted
𝑃 value*
Week 12 changeAdjusted
𝑃 value*

400-meter walk time (sec) 3 5 5 . 6 ± 1 0 . 5 (257.8–468.8) 1 . 2 ± 7 . 1 0.060.9805 3 . 3 ± 7 . 8 0.8828
Stair climb time (sec) 5 . 7 ± 0 . 3 (3.4–9.7)−0.5 ± 0.2−0.560.0036 0 . 6 ± 0 . 2 0.0013
Stair climb power (W) 2 2 1 . 6 ± 1 8 . 6 2 2 . 3 ± 7 . 1 0.620.0075 2 7 . 6 ± 8 . 5 0.0051
LLFDI: basic lower limb function 6 4 . 5 ± 1 . 7 (47.8–88.0) 1 . 8 ± 1 . 2 0.320.2279 1 . 6 ± 1 . 3 0.3657
KOOS: knee pain subscale 6 0 . 8 ± 3 . 1 (53.0–87.0) 5 . 3 ± 2 . 5 0.440.0743 6 . 4 ± 2 . 8 0.0496
KOOS: knee-related activities of daily living 6 6 . 5 ± 2 . 6 (41.8–91.2) 6 . 9 ± 2 . 4 0.560.0107 8 . 1 ± 2 . 6 0.0070
KOOS: knee-related quality of life 3 9 . 4 ± 3 . 4 (12.5–68.8) 7 . 4 ± 2 . 4 0.690.0068 7 . 0 ± 2 . 7 0.0224
SF36: bodily pain score 5 7 . 1 ± 3 . 5 (10.0–90.0) 1 0 . 5 ± 3 . 2 0.690.0040 8 . 3 ± 3 . 6 0.0453

*Dunnett-Hsu adjustment; for these repeated measures analyses, 81 observations were used, with each participant contributing data at a maximum of 3 time points.