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Volume 2013 (2013), Article ID 461486, 14 pages
Differences in Mammalian Target of Rapamycin Gene Expression in the Peripheral Blood and Articular Cartilages of Osteoarthritic Patients and Disease Activity
1Clinical Immunology Department, Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow 115522, Russia
2Department of Surgery, McGill University, Montreal, QC, Canada H3A OG4
3Osteoarthritis Laboratory, Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow 115522, Russia
4Pathomorphology Department, Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow 115522, Russia
5Statistics Department, Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow 115522, Russia
6Forensic Medicine Service, Moscow City Health Department, Moscow 111020, Russia
7Surgery Department, Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow 115522, Russia
Received 28 February 2013; Revised 12 May 2013; Accepted 12 May 2013
Academic Editor: Ruben Burgos-Vargas
Copyright © 2013 Elena V. Tchetina et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [7 citations]
The following is the list of published articles that have cited the current article.
- Elena V. Tchetina, Natalia V. Demidova, Dmitry E. Karateev, and Eugeny L. Nasonov, “Rheumatoid Factor Positivity Is Associated with Increased Joint Destruction and Upregulation of Matrix Metalloproteinase 9 and Cathepsin K Gene Expression in the Peripheral Blood in Rheumatoid Arthritic Patients Treated with Methotrexate,” International Journal of Rheumatology, vol. 2013, pp. 1–10, 2013.
- Jy He Jie-Yu, “mTOR Signaling in Aging and Aging-associated Diseases,” Progress in Biochemistry and Biophysics, vol. 41, no. 3, pp. 257–265, 2014.
- Xiaohong Wang, Heinz C. Schröder, and Werner E. G. Müller, “Polyphosphate as a metabolic fuel in Metazoa: A foundational breakthrough invention for biomedical applications,” Biotechnology Journal, 2015.
- Bandna Pal, Helal Endisha, Yue Zhang, and Mohit Kapoor, “mTOR: A Potential Therapeutic Target in Osteoarthritis?,” Drugs in R&D, 2015.
- Yu-Sheng Li, Fang-Jie Zhang, Chao Zeng, Wei Luo, Wen-Feng Xiao, Shu-Guang Gao, and Guang-Hua Lei, “Autophagy in osteoarthritis,” Joint Bone Spine, 2015.
- Mukundan Attur, Svetlana Krasnokutsky, Alexander Statnikov, Jonathan Samuels, Zhiguo Li, Olga Friese, Marie-Pierre Hellio Le Graverand-Gastineau, Leon Rybak, Virginia B. Kraus, Joanne M. Jordan, Constantin F. Aliferis, and Steven B. Abramson, “Low-Grade Inflammation in Symptomatic Knee Osteoarthritis: Prognostic Value of Inflammatory Plasma Lipids and Peripheral Blood Leukocyte Biomarkers,” Arthritis & Rheumatology, vol. 67, no. 11, pp. 2905–2915, 2015.
- Elena V. Tchetina, Karina A. Maslova, Mikhail Y. Krylov, and Valery A. Myakotkin, “Association of Bone Loss with the Upregulation of Survival-Related Genes and Concomitant Downregulation of Mammalian Target of Rapamycin and Osteoblast Differentiation-Related Genes in the Peripheral Blood of Late Postmenopausal Osteoporotic Women,” Journal of Osteoporosis, vol. 2015, pp. 1–8, 2015.