Application of a Simple In-House PCR-SSP Technique for HLA-B* 27 Typing in Spondyloarthritis Patients

Table 1

Distribution of HLA-B27 in SpA in Indian population.

Place/population	Disease	Patients	Controls	O.R	𝜒^2𝑌	P value	Ref. no.
		n+ (%PF)	n+ (%PF)
(1) Pune/WI	AS	29 (72.5)	8 (9.09)	26.00	50.76	2.22𝐸−13	[8]
(2) Pune/WI	uSpA	7 (41.17)	8 (9.09)	07.00	09.50	5.38𝐸−04	[8]
(3) Mumbai/WI	SSA	41 (51.89)	1 (0.90)	117.60	66.24	9.06𝐸−17	[9]
(4) Mumbai/WI	SSA	63 (41.72)	100 (6.17)	10.88	204.65	2.41𝐸−47	[10]
(5) Chennai/SI	AS	50 (76.92)	0 (0.0)	811.26	125.77	4.78𝐸−30	[11]
(6) Chennai/SI	ReA	22 (59.45)	0 (0.0)	361.45	80.43	2.44𝐸−20	[11]
(7) Chennai/SI	uSpA	10 (40.00)	0 (0.0)	168.68	46.97	3.06𝐸−13	[11]
(8) Varanasi/NI	SSA	48 (43.63)	4 (4.0)	18.85	42.06	3.01𝐸−11	[12]
(9) Varanasi/NI	JSpA	50 (71.42)	4 (4.0)	60.00	83.29	1.49𝐸−20	[13]
(10) Varanasi/NI	SSA	151 (68.64)	4 (4.0)	52.52	112.43	7.86𝐸−27	[14]
(11) Pune/WI	SSA	253 (56.00)	7 (3.50)	35.23	157.61	1.25𝐸−36	[15]
(12) Mumbai/WI	SpA	480 (68.57)	4 (4.40)	46.909	135.50	6.62E  − 32	Present study

NI: North India; WI: Western India; SI: South India; n+: number positive, PF: phenotype frequency, O.R: odds ratio, 𝜒²𝑌: chi-square with Yates correction.