The Application of Optical Coherence Tomography in Musculoskeletal Disease

Figure 5

PS-OCT imaging of mildly disease cartilage. (a)–(c) OCT imaging illustrating a banding pattern that is not as defined with areas of signal dropout and does not move homogenously with changes of polarization state. (e) Picrosirius red stain of the tissue which shows some areas of organized collagen but has areas where intensity of the stain is lacking. This lack of homogeneity suggests mild disease. Image courtesy of Drexler et al. [7].