Two Single-Nucleotide Polymorphisms in ADAM12 Gene Are Associated with Early and Late Radiographic Knee Osteoarthritis in Estonian Population

Figure 1

The linkage disequilibrium (LD) across the ADAM12 gene. The results of LD mapping are generated using Haploview software. The values for D^′ between each SNP are presented in each box. Black boxes denote strong LD (D^′>80%), grey boxes denote weak LD (D^′ 50–70%), and white boxes denote very weak or negligible LD (D^′<50%).