Quantitative Gait Analysis Detects Significant Differences in Movement between Osteoarthritic and Nonosteoarthritic Guinea Pig Strains before and after Treatment with Flunixin Meglumine
Figure 2
Mean values ± 95% confidence intervals for indicated gait analysis data for two guinea pig strains with varying propensity for osteoarthritis (OA-prone and OA-resistant). Data were evaluated in both strains prior to administration (baseline, time 0) of flunixin meglumine, a nonsteroidal anti-inflammatory drug (NSAID), as well as at 4, 24, and 72 hours after administration. Significant statistical differences were determined via a generalized linear model followed by Tukey’s posttests; walking speed was included as a covariate in the analyses performed on other gait parameters. values <0.05 are provided, as well as estimated differences (ED) of the means.
