The Influence of Oblique Angle Forced Exercise in Surgically Destabilized Stifle Joints Is Synergistic with Bone, but Antagonistic with Cartilage in an Ovine Model of Osteoarthritis
Table 1
Effect of exercise, surgery, and surgery + exercise, average of all compartments (mean ± SD).
Treatment group
Control
Exercise
(%)
Surgery
(%)
Surgery + exercise
(%)
BV (mm3)
1364 ± 164
1361 ± 174
(−0.2)
1474 ± 319
(8.1)
1700 ± 11.60
(24.6)
TV (mm3)
2141 ± 340
2128 ± 296
(−0.6)
2327 ± 555
(8.7)
2626 ± 19.24
(22.6)
BV/TV (%)
0.160 ± 0.006
0.160 ± 0.007
(0.5)
0.159 ± 0.006
(−0.5)
0.162 ± 0.002
(1.6)
BS/BV (mm−1)
6.56 ± 0.247
6.67 ± 0.208
(1.7)
(2.8)
(0.1)
TbTh (mm)
0.307 ± 0.012
0.302 ± 0.010
(−1.6)
(−2.7)
(−0.5)
TbN (mm−1)
1.98 ± 0.028
2.01 ± 0.053
(1.6)
1.99 ± 0.051
(0.6)
1.98 ± 0.019
(0.2)
TbSp (mm)
0.200 ± 0.011
0.197 ± 0.015
(−1.7)
0.204 ± 0.015
(2.1)
0.198 ± 0.004
(0.8)
TbPf (mm−1)
−4.51 ± 0.581
−4.66 ± 0.820
(3.2)
−4.48 ± 0.318
(−0.7)
−4.54 ± 0.135
(0.6)
MD-Tb (mgHA/cm3)
202 ± 11.7
208 ± 4.90
(2.7)
185 ± 14.3
(−8.8)
191 ± 9.04
(5.4)
MD-Cb (mgHA/cm3)
297 ± 32.2
(13.7)
(−5.7)
(2.6)
alphabetic superscripts signify values significantly different from one another (). (%): percent change from Control joint.
