EURASIP Journal on Advances in Signal Processing
Volume 2008 (2008), Article ID 520641, 11 pages
doi:10.1155/2008/520641
Research Article

Microarchitecture of a MultiCore SoC for Data Analysis of a Lab-on-Chip Microarray

G. Kornaros1,2 and S. Blionas2

1Electronic and Computer Engineering Department (ECE), Technical University of Crete, 73100 Chania, Greece
2Department of Applied Information Technology and Multimedia, Technological Educational Institute of Crete, 71004 Heraklio, Greece

Received 30 November 2007; Revised 21 May 2008; Accepted 24 June 2008

Academic Editor: P.-C. Chung

Copyright © 2008 G. Kornaros and S. Blionas. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. F. Model, T. König, C. Piepenbrock, and P. Adorján, “Statistical process control for large scale microarray experiments,” Bioinformatics, vol. 18, no. 90001, pp. S155–S163, 2002.
  2. N. Brändle, H. Bischof, and H. Lapp, “Robust DNA microarray image analysis,” Machine Vision and Applications, vol. 15, no. 1, pp. 11–28, 2003.
  3. S. Bellis, S. Blionas, J. Carrera, et al., “Competitive technology approaches for electronic hybridisation detection in a microsystem with microfluidics for diagnosis genetic tests,” in Proceedings of the 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS '06), pp. 4103–4106, New York, NY, USA, August-September 2006.
  4. M. Bicego, M. Del Rosario Martinez, and V. Murino, “A supervised data-driven approach for microarray spot quality classification,” Pattern Analysis & Applications, vol. 8, no. 1-2, pp. 181–187, 2005.
  5. V. Rodellar, F. Díaz, B. Belean, et al., “Genomic microarray processing on a FPGA for portable remote applications,” in Proceedings of the 3rd Southern Conference on Programmable Logic (SPL '07), pp. 13–18, Mar del Plata, Argentina, February 2007.
  6. F. Valafar, “Pattern recognition techniques in microarray data analysis: a survey,” Annals of the New York Academy of Sciences, vol. 980, no. 1, pp. 41–64, 2002.
  7. S. Mukherjee, “Classifying microarray data using support vector machines,” in A Practical Approach to Microarray Data Analysis, D. Berrar, W. Dubitzky, and M. Granzow, Eds., pp. 166–185, Kluwer Academic Publishers, Dordrecht, The Netherlands, 2003.
  8. R. B. Fair, A. Khlystov, V. Srinivasan, V. K. Pamula, and K. N. Weaver, “Integrated chemical/biochemical sample collection, pre-concentration, and analysis on a digital microfluidic lab-on-a-chip platform,” in Lab-on-a-Chip: Platforms, Devices, and Applications, L. A. Smith and D. Sobek, Eds., vol. 5591 of Proceedings of SPIE, pp. 113–124, Philadelphia, Pa, USA, October 2004.
  9. T. Xu and K. Chakrabarty, “A cross-referencing-based droplet manipulation method for high-throughput and pin-constrained digital microfluidic arrays,” in Proceedings of the Design, Automation & Test in Europe Conference & Exhibition (DATE '07), pp. 1–6, Nice, France, April 2007.
  10. W. L. Hwang, F. Su, and K. Chakrabarty, “Automated design of pin-constrained digital microfluidic arrays for lab-on-a-chip applications,” in Proceedings of the 43rd ACM/IEEE Design Automation Conference (DAC '06), pp. 925–930, San Francisco, Calif, USA, July 2006.
  11. I. Ragoussis, M. Paolucci, and L. Lornie, “D5.1Development of a robust mutation, detection protocol,” Micro2DNA ICT-027333-STP EC project, July 2007.
  12. C. Zhang, J. Xu, W. Ma, and W. Zheng, “PCR microfluidic devices for DNA amplification,” Biotechnology Advances, vol. 24, no. 3, pp. 243–284, 2006.
  13. A.-C. Syvänen, “Accessing genetic variation: genotyping single nucleotide polymorphisms,” Nature Reviews Genetics, vol. 2, no. 12, pp. 930–942, 2001.
  14. D. J. Cutler, M. E. Zwick, M. M. Carrasquillo, et al., “High-throughput variation detection and genotyping using microarrays,” Genome Research, vol. 11, no. 11, pp. 1913–1925, 2001.
  15. T. R. Hughes, M. Mao, A. R. Jones, et al., “Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer,” Nature Biotechnology, vol. 19, no. 4, pp. 342–347, 2001.
  16. J. C. Jackson, A. P. Morrison, D. Phelan, and A. Mathewson, “A novel silicon Geiger-mode avalanche photodiode,” in Proceedings of the IEEE International Electron Devices Meeting (IEDM '02), pp. 797–800, San Francisco, Calif, USA, December 2002.
  17. Y. H. Yang, M. J. Buckley, S. Dudoit, and T. P. Speed, “Comparison of methods for image analysis on cDNA microarray data,” Journal of Computational and Graphical Statistics, vol. 11, no. 1, pp. 108–136, 2002.
  18. G. Kornaros, et al., “Architecture of a consumer lab-on-chip for pharmacogenomics,” in Proceedings of the IEEE International Conference on Consumer Electroncs (ICCE '08), Las Vegas, USA, January 2008.