Advances in Toxicology / 2014 / Article / Tab 4 / Research Article
Compound-Specific Toxicities Detected in CFU-GM, Rat Kidney NRK Cells, Rat Bladder RBLAK Cells, and Rat Liver Slices following Batracylin or N-Acetyl Batracylin Exposure Table 4 % nuclei area positive for γ -H2AX staining.
Treatment μ MNRK RBLAK 6 hr 24 hr 72 hr 6 hr 24 hr 72 hr Vehicle 0 3.3 ± 0.6 3.0 ± 0.7 1.3 ± 0.1 1.9 ± 0.2 2.0 ± 0.3 2.9 ± 0.6 BAT 3.13 4.8 ± 1.0 5.2 ± 0.2 2.6 ± 0.5 9.5 ± 1.5 12.2 ± 0.3 7.1 ± 1.9 6.25 5.5 ± 0.7 6.2 ± 0.7 3.4 ± 0.6 8.0 ± 1.4 10.3 ± 0.5 6.3 ± 1.5 12.5 7.9 ± 0.8 8.9 ± 1.0 5.1 ± 0.5 9.1 ± 1.3 8.8 ± 0.8 6.3 ± 1.6 25 19.0 ± 2.6 15.9 ± 1.7 6.7 ± 0.8 10.9 ± 1.8 5.2 ± 0.4 7.3 ± 0.7 50 30.9 ± 3.3 26.7 ± 2.2 8.9 ± 2.1 15.3 ± 1.9 12.1 ± 0.2 1.5 ± 0.4 NAB 0.31 3.6 ± 0.3 2.6 ± 0.5 1.6 ± 0.2 1.5 ± 0.3 1.9 ± 0.1 3.4 ± 0.8 0.63 3.4 ± 0.6 2.9 ± 0.3 1.4 ± 0.2 1.8 ± 0.5 2.3 ± 0.2 4.5 ± 2.1 1.25 3.7 ± 0.7 3.2 ± 1.4 1.8 ± 0.4 2.8 ± 0.6 2.1 ± 0.6 4.3 ± 0.9 2.5 3.7 ± 0.2 4.4 ± 2.3 2.1 ± 0.3 3.2 ± 0.2 2.9 ± 0.6 4.7 ± 0.9 5 4.3 ± 0.3 3.4 ± 1.0 2.5 ± 0.4 4.8 ± 1.2 4.3 ± 0.7 7.2 ± 2.3 Etoposide 3.13 40.7 ± 1.2 17.9 ± 1.4 13.2 ± 1.5 40.7 ± 2.2 40.9 ± 0.6 34.8 ± 9.0 25 74.6 ± 4.6 42.0 ± 3.1 27.3 ± 2.8 68.1 ± 2.4 35.5 ± 10.2 19.8 ± 0.9