Differential Effect of Isooctane Doses on HaCaT and HeLa: A Multimodal Analysis

Figure 1

Phase contrast microscopic images under 40x objective of HaCaT (a–d) and HeLa (a1–d1) cells, respectively, of control and 5 hrs after exposure to IO doses. In case of HaCaT, in comparison to control (a) and 4% IO (b) groups, 6% (c) and 8% (d) IO groups depicted drastic changes in the dead cell population with increase in intercellular space as seen in the magnified portion. Phase contrast microscopic images under 40x objectives (a1–d1) of HeLa cell of control and after 5 hrs exposure to different IO doses. In comparison to control (a1), no remarkable changes can be observed in the experimental groups (b1–d1) (cell death: yellow arrow); (cell size: red arrow); (intracellular spaces: orange arrow).