Chemical Exposure Generates DNA Copy Number Variants and Impacts Gene Expression

Figure 5

CNVs generated by chemical exposure. (a) Exposure to EMS resulted in 44 CNVs among all treatments and consisted of 11 CNVs with overlapping genomic locations. Considering genomic location overlap, 29 different copy number variable regions were identified and included both gains (12; green bars) and losses (17; red bars). Length of bar indicates frequency. (b) Ara-C exposure resulted in 18 CNVs among the treatments including 13 gains (green bars) and 5 losses (red bars). There were no overlapping CNVs among the Ara-C treatments.

(a)

(b)