Familial Syndromes Coupling with Small Renal Masses

Table 4

FRC versus autosomal dominant (AD) forms of kidney cancer (adapted from Zbar et al. [3]).

Disease	Inheritance mode	Age at onset	Tumor multiciplicity	Histology
FRC	Complex	Late	Single	varied
VHL	AD	Adolescence	Bilat, multiple	Clear cell
HPRC	AD	40–49 years	Bilat, multiple	Papillary type 1
BHD	AD	30–39 years	Bilat, multiple	Chromophobe/hybrid oncocytic
HLRCC	AD	10–20 years	Single or multiple	Renal cell Ca, HLRCC type