Bladder Dysfunction and Vesicoureteral Reflux

Table 3

Impact of treatment of bladder dysfunction on spontaneous resolution of VUR.

Reference	Age (y)	Patients (number)	VUR grade	Bladder dysfunction	Treatment	Follow/up (y)	Resolution (downgrading)	Controls resolution (downgrading)
Koff & Murtagh 1983 [18]	2–14	62	I-IV	OAB	Anticholonergics	4	44% (16%)	17% (0%)
Scholtmeijer & Griffiths 1990 [33]		25	I-IV	OAB	Anticholinergics	1	37% (22%)	No controls
Scholtmeijer & Nijman 1994 [19]	0.1–15	39	I-IV	OAB	Anti-cholinergics	3	38% (38%)	40% (16%)
Willemsen & Nijman 2000 [34]	0.1–15	102	I-V	OAB	Anti-cholinergics	5	51%	55%
Palmer et al. 2002 [35]	6–10	25	I-III	DV	Biofeedback	1	55% (16%)	No controls
Kibar et al. 2007 [36]	7.2	78	I-IV	DV	Biofeedback	0.5	63% (29%)	No controls
Homsy 1985 [32]	4–11	35	I-IV	OAB + DV	Oxybutynine	2.5	50% (22%)	No controls
Snodgrass 1998 [15]	3–10	128		OAB + DV	Oxybutynine		45%	61%