Review Article

Review of Topical Treatment of Upper Tract Urothelial Carcinoma

Table 1

Mechanism of immunotherapy agents.

BCGInflammatory host response
Release of cytokines

InterferonLymphocyte activation
Cytokine release
Phagocyte stimulation
Antiproliferative actions
Antiangiogenic

ThiotepaAlkylating agent
Crosslinks nucleic acids

Mitomycin CInhibits DNA synthesis

GemcitabineDeoxyctidine analog
Inhibits DNA synthesis