Management of Bladder Cancer following Solid Organ Transplantation

Table 2

Characteristics of patients with muscle-invasive TCC of the bladder.

Patient number	1	2	3	4
Age at transplant	38	58	60	66
Type of transplant	Renal	Liver	Renal	Renal
Age at diagnosis	44	60	63	70
Immunosuppression	FK, Pred	FK, MMF, Pred	FK, Pred	FK, Pred
Pathologic stage	T3aN0M0	T3N2M0	T2N0M0	T2N0M1
Histology	TCC, CIS	TCC	TCC	TCC
Grade	High	High	High	High
Treatment	Cystectomy, allograft nephrostomy	Cystectomy, neobladder	Palliative XRT, Ileal conduit	Palliative XRT
Followup (months)	24	36	16	12
Metastasis (months)	None	None	None	Liver, pulmonary (12)
Status	Alive	Alive	Deceased (DIC)	Deceased

FK: tacrolimus; MMF: mycophenolate mofetil; Pred: prednisone; CIS: carcinoma in site; TURBT: transurethral resection of bladder tumor; DIC: disseminated intravascular coagulation; XRT: external beam radiotherapy.