Prostate-Specific Membrane Antigen-Based Therapeutics

Table 1

Radionuclide properties.

Radionuclide properties	^131I	^90Y	^177Lu
Physical half-life (days)	8.05	2.67	6.7
Beta particles (mEv)
max	0.61	2.280	0.497
average	0.20	0.935	0.149
Range in tissue (mm)
max	2.4	12.0	2.20
average	0.4	2.7	0.25
Gamma emission (mEv)	0.364	None	0.113–0.208
Optimal size of tumor when targeted for curability [25]	3–5 mm	28–42 mm	1–3 mm
Comments	Cannot be used with internalizing mAb’s	Lacks gamma emissions (cannot use for imaging)