Table 1: Immunoreactivity of APP in human testicular specimens.

APP intensity score Number of cases (%)
Normal testicular tissue SGCT NGCT

025 (80.6) 36 (87.8) 14 (60.9)
1+ 6 (19.4) 1 (0.02) 0 (0)
2+ 0 (0) 3 (0.07) 5 (21.7)
3+ 0 (0) 1 (0.02) 4 (17.4)

Total 314123

APP: amyloid precursor protein, SGCT: seminomatous germ cell tumor, NGCT: nonseminomatous germ cell tumor. Intensity score was rated from 0 to 3+ and defined as 0: no immunostaining, 1+: weak intensity, 2+: moderate intensity, 3+: strong intensity. “0” and “1+” are defined as “negative immunoreactivity.” “2+” and “3+” are defined as “positive immunoreactivity.” Numbers in boldface indicate negative immunoreactivity while those in light face indicate positive immunoreactivity.