Research Article
Differences in Upgrading of Prostate Cancer in Prostatectomies between Community and Academic Practices
Table 2
Proportion of cases with Gleason upgrading at RP based on pathologic and clinical characteristics.
| | | Upgrading | P-value* | | | No (%) | Yes (%) |
| | Age at biopsy | | | <0.01 | | <60 | 436 (49) | 184 (41) | | | 60–69 | 371 (41) | 199 (44) | | | ≥70 | 88 (10) | 69 (15) | | | PSA | | | <0.01 | | <4.0 | 208 (23) | 66 (15) | | | 4–9.9 | 542 (61) | 285 (63) | | | ≥10.0 | 114 (13) | 93 (21) | | | Prostate size (cc) | | | 0.35 | | <35 | 196 (22) | 117 (26) | | | 35–44 | 234 (26) | 122 (27) | | | 44–56 | 218 (24) | 107 (24) | | | >56 | 220 (25) | 98 (22) | | | Number of cores obtained | | | 0.02 | | ≤6 | 373 (41) | 155 (34) | | | 6–9 | 98 (11) | 50 (11) | | | 10+ | 424 (47) | 248 (55) | | | Number of positive cores | | | 0.03 | | One | 232 (26) | 83 (18) | | | Two | 163 (18) | 96 (21) | | | Three | 135 (15) | 70 (15) | | | Four or more | 202 (23) | 114 (27) | | | Biopsy Gleason sum | | | <0.001 | | 570 (64) | 335 (74) | | | 325 (36) | 118 (26) | |
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P-value from chi-square test.
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