Table 2: Proportion of cases with Gleason upgrading at RP based on pathologic and clinical characteristics.

UpgradingP-value*
No (%)Yes (%)

Age at biopsy<0.01
 <60436 (49)184 (41)
 60–69 371 (41)199 (44)
 ≥70 88 (10)69 (15)
PSA <0.01
 <4.0208 (23)66 (15)
 4–9.9 542 (61)285 (63)
 ≥10.0114 (13)93 (21)
Prostate size (cc) 0.35
 <35196 (22)117 (26)
 35–44 234 (26)122 (27)
 44–56 218 (24)107 (24)
 >56220 (25)98 (22)
Number of cores obtained0.02
 ≤6373 (41)155 (34)
 6–998 (11)50 (11)
 10+ 424 (47)248 (55)
Number of positive cores 0.03
 One 232 (26)83 (18)
 Two163 (18)96 (21)
 Three135 (15)70 (15)
 Four or more 202 (23)114 (27)
Biopsy Gleason sum<0.001
570 (64)335 (74)
325 (36)118 (26)

P-value from chi-square test.