Table 3: Multivariate logistic regression for risk of Gleason upgrading at radical prostatectomy.

Odds ratio*95% CI

Site of biopsy
 Academic1.00Referent
 Community0.910.68–1.22 (P = 0.53)
Age at biopsy
 <601.00Referent
 60–691.381.061.82 (P = 0.02)
 ≥702.821.874.28 (P < 0.01)
PSA
 <4.01.00Referent
 4–9.91.771.272.47 (P < 0.01)
 ≥104.082.11–6.35 (P < 0.01)
Prostate size (cc)
 <351.00Referent
 35–440.800.56–1.12 (P = 0.2)
 44–560.650.45–0.93 (P = 0.02)
 >560.510.35–0.74 (P = 0.04)
Total number of biopsy cores
 <101.00Referent
 ≥100.850.61–1.19 (P = 0.5)
Number of positive cores
 One1.00Referent
 Two1.701.15–2.50 (P = 0.01)
 Three1.531.00–2.34 (P = 0.04)
 Four or more1.961.33–2.89 (P < 0.01)
Biopsy Gleason sum
1.00Referent
0.390.29–0.52 (P < 0.01)

Odds ratios adjusted for all other variables in the table.