Table 2: Final multivariable linear regression models for the SISTEr and TOMUS trials with outcome of UDI-I.

CovariateSISTErTOMUS
valueEstimate** valueEstimate**

Race/ethnicity0.0010.18
 Hispanic41.3040.46
 Non-Hispanic white48.1741.24
 Non-Hispanic black55.6747.06
 Non-Hispanic other52.6547.80
Education0.006<0.0001
 <High school56.2346.50
 High school/GED50.1950.52
 >High school49.0445.27
 BA/BS42.9038.20
 Grad/Prof48.8740.20
UI Severity (PGI-S)*<0.0001.
 NormalN/A42.11
 MildN/A35.08
 ModerateN/A45.57
 SevereN/A53.80
Charlson Comorbidity Index (CCI)*0.0003
 0N/A39.35
 1N/A42.11
 2+ N/A50.97
UDI stress score<0.00010.170.060.08
Body mass index0.0020.440.340.13
IIQ total <0.00010.11<0.00010.09
Pad weight (10 g per unit)0.030.230.0040. 39

UI severity and number of comorbidities were not collected in the SISTEr trial.
**For categorical predictors, least squares means are reported, and for continuous covariates, regression coefficients are reported.