Table 3: Final multivariable linear regression models for the SISTEr and TOMUS trials with outcome urge symptoms from the MESA scale.

CovariateSISTErTOMUS
valueEstimate** valueEstimate**

Education<0.00010.002
 <High school8.217.12
 High school/GED6.507.15
 >High school6.526.65
 BA/BS5.345.62
 Grad/Prof6.485.90
Depression (PHQ-9)*N/A0.01
 <106.06
 10+ depression6.91
MESA stress score<0.00010.41<0.00010.41
Age (10 years per unit)0.0010.42<0.00010.54
Pad weight (10 g per unit)0.0010.050.00070.07

Depression information was not collected in the SISTEr trial.
**For categorical covariates, least squares means are reported, and for continuous covariates, regression coefficients are reported.