Higher Prostate Weight Is Inversely Associated with Gleason Score Upgrading in Radical Prostatectomy Specimens

Table 2

Univariate logistic regression analysis to preoperatively predict Gleason discordance.

Variable	Categories	𝑃 value	Odds ratio	CI 95% OR
Race	White*	—	1.00	—
	Black	0.281	1.38	0.77–2.49
Age	Years	0.049	1.035	1.001–1.070
Clinical stage	T1c*	—	1.00	—
	T2a	0.030	1.79	1.06–3.03
	T2b	0.438	0.75	0.37–1.55
	T2c	0.128	5.11	0.62–41.81
Clinical stage (T1c × T2)	T1c*	—	1.00	—
	T2	0.092	1.49	0.94–2.37
PSA	ng/dL	<0.001	1.080	1.032–1.130
PSA (> or <10 ng/ml)	<10 ng/mL*	—	1.00	—
	>10 ng/mL	<0.001	2.48	1.50–4.11
Prostate weight	g	0.005	0.984	0.973–0.995
PSA density	0.1 unity	<0.001	1.713	1.394–2.104
Biopsy Gleason score	≤6*	—	1.00	—
	7	<0.001	19.13	7.50–48.80

 *Categories of reference; CI: confidence interval; OR: odds ratio.