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Advances in Urology
Volume 2013 (2013), Article ID 836121, 6 pages
Weight Loss and Melatonin Reduce Obesity-Induced Oxidative Damage in Rat Testis
1Gaziosmanpasa University, Faculty of Medicine, Department of Urology, 60100 Tokat, Turkey
2Sakarya University, Faculty of Medicine, Department of Biostatistics and Medical informatics, 54100 Sakarya, Turkey
3Gaziosmanpasa University, Faculty of Medicine, Department of Biochemistry, 60100 Tokat, Turkey
4Gaziosmanpasa University, Faculty of Medicine, Department of Pathology, 60100 Tokat, Turkey
Received 26 June 2013; Accepted 7 August 2013
Academic Editor: James A. Brown
Copyright © 2013 Dogan Atilgan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- P. G. Kopelman, “Obesity as a medical problem,” Nature, vol. 404, no. 6778, pp. 635–643, 2000.
- WHO, “World Health Organization Part I: the problem of overweight and obesity. World Health Organization. Obesity: preventing and managing the global epidemic,” WHO Technical Report Series 894, Geneva, Switzerland, 2000.
- F. Hammiche, J. S. Laven, J. M. Twigt, W. P. Boellaard, E. A. Steegers, and R. P. Steegers-Theunissen, “Body mass index and central adiposity are associated with sperm quality in men of subfertile couples,” Human Reproduction, vol. 27, no. 8, pp. 2365–2372, 2012.
- L. Sekhavat and M. R. Moein, “The effect of male body mass index on sperm parameters,” Aging Male, vol. 13, no. 3, pp. 155–158, 2010.
- T. K. Jensen, A.-M. Andersson, N. Jørgensen et al., “Body mass index in relation to semen quality and reproductive hormones among 1,558 Danish men,” Fertility and Sterility, vol. 82, no. 4, pp. 863–870, 2004.
- U. Paasch, S. Grunewald, J. Kratzsch, and H.-J. Glander, “Obesity and age affect male fertility potential,” Fertility and Sterility, vol. 94, no. 7, pp. 2898–2901, 2010.
- N. Sermondade, C. Faure, L. Fezeu et al., “Obesity and increased risk for oligozoospermia and azoospermia,” Archives of Internal Medicine, vol. 172, no. 5, pp. 440–442, 2012.
- D. P. Evenson, L. K. Jost, D. Marshall et al., “Utility of the sperm chromatin structure assay as a diagnostic and prognostic tool in the human fertility clinic,” Human Reproduction, vol. 14, no. 4, pp. 1039–1049, 1999.
- J. E. Chavarro, T. L. Toth, D. L. Wright, J. D. Meeker, and R. Hauser, “Body mass index in relation to semen quality, sperm DNA integrity, and serum reproductive hormone levels among men attending an infertility clinic,” Fertility and Sterility, vol. 93, no. 7, pp. 2222–2231, 2010.
- A. S. Aggerholm, A. M. Thulstrup, G. Toft, C. H. Ramlau-Hansen, and J. P. Bonde, “Is overweight a risk factor for reduced semen quality and altered serum sex hormone profile?” Fertility and Sterility, vol. 90, no. 3, pp. 619–626, 2008.
- F. H. Duits, M. Van Wely, F. Van Der Veen, and J. Gianotten, “Healthy overweight male partners of subfertile couples should not worry about their semen quality,” Fertility and Sterility, vol. 94, no. 4, pp. 1356–1359, 2010.
- A. A. MacDonald, G. P. Herbison, M. Showell, and C. M. Farquhar, “The impact of body mass index on semen parameters and reproductive hormones in human males: a systematic review with meta-analysis,” Human Reproduction Update, vol. 16, no. 3, Article ID dmp047, pp. 293–311, 2009.
- H. Kodama, H. Kasai, R. Yamaguchi, T. Tanaka, and J. Fukuda, “Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients,” Fertility and Sterility, vol. 68, no. 3, pp. 519–524, 1997.
- J. N. Egwurugwu, A. Nwafor, C. P. Chike et al., “The relationship between body mass index, semen and sex hormones in adult male,” Nigerian Journal of Physiological Sciences, vol. 26, pp. 29–34, 2011.
- I. Fejes, S. Koloszár, Z. Závaczki, J. Daru, J. Szöllösi, and A. Pál, “Effect of body weight on testosterone/estradiol ratio in oligozoospermic patients,” Archives of Andrology, vol. 52, no. 2, pp. 97–102, 2006.
- C. Migdal and M. Serres, “Reactive oxygen species and oxidative stress,” Medecine/Sciences, vol. 27, no. 4, pp. 405–412, 2011.
- S. C. Sikka, “Relative impact of oxidative stress on male reproductive function,” Current Medicinal Chemistry, vol. 8, no. 7, pp. 851–862, 2001.
- F. Erdemir, D. Atilgan, F. Markoc, O. Boztepe, B. Suha-Parlaktas, and S. Sahin, “The effect of diet induced obesity on testicular tissue and serum oxidative stress parameters,” Actas Urologicas Espanolas, vol. 36, no. 3, pp. 153–159, 2012.
- D. X. Tan, “Melatonin: a potent, endogenous hydroxyl radical scavenger,” Endocrine Journal, vol. 1, pp. 57–60, 1993.
- Y. Sun, L. W. Oberley, and Y. Li, “A simple method for clinical assay of superoxide dismutase,” Clinical Chemistry, vol. 34, no. 3, pp. 497–500, 1988.
- H. Esterbaur and K. H. Cheeseman, “Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hyroxynonenal,” in Methods in Enzimology Oxygen Radicals in Biological Systems, L. Packer and A. N. Glazer, Eds., vol. 186, pp. 407–421, Academic Press, New York, NY, USA, 1990.
- R. L. Levine, D. Garland, C. N. Oliver et al., “Determination of carbonyl content in oxidatively modified proteins,” Methods in Enzymology, vol. 186, pp. 464–478, 1990.
- N. Sermondade, C. Faure, L. Fezeu, A. G. Shayeb, J. P. Bonde, T. K. Jensen, et al., “BMI in relation to sperm count: an updated systematic review and collaborative meta-analysis,” Human Reproduction Update, vol. 19, no. 3, pp. 221–231, 2013.
- D.-D. Qin, W. Yuan, W.-J. Zhou, Y.-Q. Cui, J.-Q. Wu, and E.-S. Gao, “Do reproductive hormones explain the association between body mass index and semen quality?” Asian Journal of Andrology, vol. 9, no. 6, pp. 827–834, 2007.
- S. P. Weisberg, D. McCann, M. Desai, M. Rosenbaum, R. L. Leibel, and A. W. Ferrante Jr., “Obesity is associated with macrophage accumulation in adipose tissue,” Journal of Clinical Investigation, vol. 112, no. 12, pp. 1796–1808, 2003.
- H. Xu, G. T. Barnes, Q. Yang et al., “Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance,” Journal of Clinical Investigation, vol. 112, no. 12, pp. 1821–1830, 2003.
- S. Furukawa, T. Fujita, M. Shimabukuro et al., “Increased oxidative stress in obesity and its impact on metabolic syndrome,” Journal of Clinical Investigation, vol. 114, no. 12, pp. 1752–1761, 2004.
- R. J. Aitken, A. L. Ryan, M. A. Baker, and E. A. McLaughlin, “Redox activity associated with the maturation and capacitation of mammalian spermatozoa,” Free Radical Biology and Medicine, vol. 36, no. 8, pp. 994–1010, 2004.
- S. S. R. Allamaneni, C. K. Naughton, R. K. Sharma, A. J. Thomas Jr., and A. Agarwal, “Increased seminal reactive oxygen species levels in patients with varicoceles correlate with varicocele grade but not with testis size,” Fertility and Sterility, vol. 82, no. 6, pp. 1684–1686, 2004.
- A. Agarwal and R. A. Saleh, “Role of oxidants in male infertility: rationale, significance, and treatment,” Urologic Clinics of North America, vol. 29, no. 4, pp. 817–827, 2002.
- A. Agarwal, S. Hamamah, and M. Shekarriz, “Reactive oxygen species and fertilizing capacity of spermatozoa,” Contraception, Fertilité, Sexualité, vol. 22, pp. 327–330, 1994.
- A. A. Zalata, A. H. Ahmed, S. S. R. Allamaneni, F. H. Comhaire, and A. Agarwal, “Relationship between acrosin activity of human spermatozoa and oxidative stress,” Asian Journal of Andrology, vol. 6, no. 4, pp. 313–318, 2004.
- P. Dandona, P. Mohanty, H. Ghanim et al., “The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation,” Journal of Clinical Endocrinology and Metabolism, vol. 86, no. 1, pp. 355–362, 2001.
- A. Mohn, M. Catino, R. Capanna, C. Giannini, M. Marcovecchio, and F. Chiarelli, “Increased oxidative stress in prepubertal severely obese children: effect of a dietary restriction-weight loss program,” Journal of Clinical Endocrinology and Metabolism, vol. 90, no. 5, pp. 2653–2658, 2005.
- L. B. Håkonsen, A. M. Thulstrup, A. S. Aggerholm et al., “Does weight loss improve semen quality and reproductive hormones? Results from a cohort of severely obese men,” Reproductive Health, vol. 8, article 24, 2011.