Reduced Cardiovascular Capacity and Resting Metabolic Rate in Men with Prostate Cancer Undergoing Androgen Deprivation: A Comprehensive Cross-Sectional Investigation
Table 2
Body composition and blood markers for the short- and longer-term androgen deprivation groups.
Variable
<3 months Mean ± SD
≥3 months Mean ± SD
Mean difference (95% CI)
value
Lean tissue mass (kg)
Whole body
60.1 ± 7.5
58.0 ± 8.6
2.1 (−1.0, 5.2)
0.184
Appendicular
25.6 ± 3.3
24.5 ± 3.9
1.1 (−0.3, 2.5)
0.112
Fat mass (kg)
Whole body
23.1 ± 7.3
24.6 ± 8.3
−1.5 (−4.5, 1.4)
0.307
Trunk
12.4 ± 4.5
12.9 ± 5.8
−0.5 (−2.5, 1.5)
0.627
Body fat %
26.4 ± 5.1
28.3 ± 5.2
−1.9 (−4.0, 0.1)
0.053
Blood markers
HbA1C (%)
6.4 ± 3.7
6.1 ± 1.0
0.3 (−0.8, 1.3)
0.638
Testosterone (pg⋅mL−1)
1.3 ± 1.5
1.5 ± 3.4
−0.2 (−1.2, 0.8)
0.651
Prostate specific antigen (ng⋅mL−1)
1.2 ± 1.7
1.4 ± 2.6
−0.2 (−1.1, 0.7)
0.659
Insulin (mU/L)
11.2 ± 6.7
9.2 ± 4.3
2.0 (−0.3, 4.2)
0.085
Triglycerides (mmol/L)
1.3 ± 0.6
1.4 ± 0.7
−0.1 (−0.3, 0.1)
0.393
LDL cholesterol (mmol/L)
2.8 ± 0.9
2.9 ± 1.0
−0.1 (−0.5, 0.3)
0.575
HDL cholesterol (mmol/L)
1.3 ± 0.4
1.4 ± 0.4
−0.1 (−0.3, 0.1)
0.269
Total cholesterol (mmol/L)
4.7 ± 1.1
4.9 ± 1.0
−0.2 (−0.6, 0.2)
0.287
Glucose (mmol/L)
5.5 ± 1.1
5.9 ± 1.9
−0.4 (−1.0, 0.2)
0.216
C-reactive protein (mg/L)
2.9 ± 3.3
2.5 ± 2.0
0.4 (−0.7, 1.5)
0.469
HbA1C: glycated haemoglobin; LDL: low density lipoprotein; HDL: high density lipoprotein.
