Prevalence, Risk Factors, and Clinical Relevance of Fluoroquinolone-Resistant Organisms in Rectal Cultures: Should We Target Antibiotic Prophylaxis Prior to Prostate Biopsy?

Table 2

Limitations of studies examining targeted therapy for prostate biopsies.

Study bias	Risk	Advice
Not reporting minor infectious complications	Underreporting of infectious complications	Reporting of prostatitis, epididymitis, pyelonephritis, uncomplicated urinary tract infections, and sepsis and septic shock
Insufficient length of follow-up		Follow-up period of at least 30 days
Inadequate registration method		Direct patient contact through a telephone call or follow-up consultation
Practitioner decides in which patient rectal cultures are taken	Biased study population: risk of excluding frail patients	Prospective randomisation after obtaining informed consent