Clinical Study

Effectiveness of Methylcobalamin and Folinic Acid Treatment on Adaptive Behavior in Children with Autistic Disorder Is Related to Glutathione Redox Status

Figure 3

Significant relationships between the change in the glutathione redox status (reduced-to-oxidized glutathione ratio) and change in subscales of the Vineland Adaptive Behavior Scale (VABS) subscales. An improvement in glutathione redox status was associated with improvement in (a) expressive communication ( ), (b) personal daily living skills ( ), (c) domestic daily living skills ( ), (d) interpersonal social skills ( ), (e) play-leisure social skills ( ), and (f) coping social skills ( ). The moderating effect of glutathione redox status on the VABS subscale is provided in the graph as a representation of the relationship between the variables. Since the linear models examining the moderating effect of glutathione redox status on the VABS subscale takes into account age, simple correlation coefficients would not be accurate for inclusion in the graphs.
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