A Systemic Network Triggered by Human Cytomegalovirus Entry
Figure 4
Contribution of individual genes to properties of the network enhanced by HCMV entry. Extracellular and membrane components of the network enhanced by HCMV entry (Figure 3) were individually knockedout in silico, and the effects of such knock out were calculated. Only genes with at least two direct neighbors in the network were knocked out because genes with only one direct neighbor or without neighbors are located at the end-terminal in the network and would not significantly affect the network architecture. (a) Contribution of individual genes to network connectivity. (b) Contribution of individual genes to network diameter.
