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Advances in Virology
Volume 2011 (2011), Article ID 281425, 5 pages
Testing Strategies for Detection of Xenotropic Murine Leukemia Virus-Related Virus Infection
Laboratory of Molecular Virology, CBER, Food and Drug Administration, Bethesda, MD 20892, USA
Received 10 March 2011; Revised 18 May 2011; Accepted 10 June 2011
Academic Editor: Myra McClure
Copyright © 2011 Shixing Tang and Indira K. Hewlett. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- A. Urisman, R. J. Molinaro, N. Fischer et al., “Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant,” PLoS Pathogens, vol. 2, no. 3, article e25, 2006.
- V. C. Lombardi, F. W. Ruscetti, J. D. Gupta et al., “Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome,” Science, vol. 326, no. 5952, pp. 585–589, 2009.
- E. Callaway, “Virology: fighting for a cause,” Nature, vol. 471, no. 7338, pp. 282–285, 2011.
- J. Carlowe, “Chronic fatigue syndrome is not caused by XMRV virus, study shows,” The British Medical Journal, vol. 341, article c7358, 2010.
- J. M. Coffin and J. P. Stoye, “Virology. A new virus for old diseases?” Science, vol. 326, no. 5952, pp. 530–531, 2009.
- J. Cohen, “Retrovirology. More negative data for link between mouse virus and human disease,” Science, vol. 331, no. 6022, pp. 1253–1254, 2011.
- M. McClure and S. Kaye, “Can detection of xenotropic murine leukemia virus-related virus be linked to chronic fatigue syndrome?” Expert Review of Molecular Diagnostics, vol. 10, no. 5, pp. 537–539, 2010.
- M. McClure and S. Wessely, “Chronic fatigue syndrome and human retrovirus XMRV,” The British Medical Journal, vol. 340, article c1099, 2010.
- R. H. Silverman, C. Nguyen, C. J. Weight, and E. A. Klein, “The human retrovirus XMRV in prostate cancer and chronic fatigue syndrome,” Nature Reviews Urology, vol. 7, no. 7, pp. 392–402, 2010.
- M. A. Wainberg and K.-T. Jeang, “XMRV as a human pathogen?” Cell Host & Microbe, vol. 9, no. 4, pp. 260–262, 2011.
- R. A. Weiss, “A cautionary tale of virus and disease,” BMC Biology, vol. 8, article 124, 2010.
- S. C. Lo, N. Pripuzova, B. Li et al., “Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors,” Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 36, pp. 15874–15879, 2010.
- R. A. Smith, “Contamination of clinical specimens with MLV-encoding nucleic acids: implications for XMRV and other candidate human retroviruses,” Retrovirology, vol. 7, no. 1, article 112, 2010.
- J. P. Stoye, R. H. Silverman, C. A. Boucher, and S. F. Le Grice, “The xenotropic murine leukemia virus-related retrovirus debate continues at first international workshop,” Retrovirology, vol. 7, no. 1, article 113, 2010.
- J. A. Mikovits, V. C. Lombardi, M. A. Pfost, K. S. Hagen, and F. W. Ruscetti, “Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome,” Virulence, vol. 1, no. 5, pp. 386–390, 2010.
- J. A. Mikovits, Y. Huang, M. A. Pfost et al., “Distribution of xenotropic murine leukemia virus-related virus (XMRV) infection in chronic fatigue syndrome and prostate cancer,” AIDS Reviews, vol. 12, no. 3, pp. 149–152, 2010.
- T. Roe, T. C. Reynolds, G. Yu, and P. O. Brown, “Integration of murine leukemia virus DNA depends on mitosis,” The EMBO Journal, vol. 12, no. 5, pp. 2099–2108, 1993.
- B. P. Danielson, G. E. Ayala, and J. T. Kimata, “Detection of xenotropic murine leukemia virus-related virus in normal and tumor tissue of patients from the southern United States with prostate cancer is dependent on specific polymerase chain reaction conditions,” Journal of Infectious Diseases, vol. 202, no. 10, pp. 1470–1477, 2010.
- M. J. Robinson, O. W. Erlwein, S. Kaye et al., “Mouse DNA contamination in human tissue tested for XMRV,” Retrovirology, vol. 7, no. 1, article 108, 2010.
- B. Oakes, A. K. Tai, O. Cingoz et al., “Contamination of human DNA samples with mouse DNA can lead to false detection of XMRV-like sequences,” Retrovirology, vol. 7, no. 1, article 109, 2010.
- E. Sato, R. A. Furuta, and T. Miyazawa, “An endogenous murine leukemia viral genome contaminant in a commercial RT-PCR Kit is amplified using standard primers for XMRV,” Retrovirology, vol. 7, no. 1, article 110, 2010.
- S. Hue, E. R. Gray, A. Gall et al., “Disease-associated XMRV sequences are consistent with laboratory contamination,” Retrovirology, vol. 7, no. 1, article 111, 2010.
- R. Schlaberg, D. J. Choe, K. R. Brown, H. M. Thaker, and I. R. Singh, “XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors,” Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 38, pp. 16351–16356, 2009.
- F. J. van Kuppeveld, A. S. Jong, K. H. Lanke et al., “Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retrospective analysis of samples from an established cohort,” The British Medical Journal, vol. 340, article c1018, 2010.
- K. S. Jones, Y. K. Huang, C. Petrow-Sadowski, et al., “Evidence for sequeence variation in XMRV,” in Proceedings of the Annual Meeting on Retroviruses, Cold Spring Harbor Laboratory, New York, NY, USA, abstract 13, 2010.
- T. Paprotka, K. A. Delviks-Frankenberry, O. Cingoz, et al., “Recombinant origin of the retrovirus XMRV,” Science, vol. 333, no. 6038, pp. 97–101, 2011.
- A. Dupressoir and T. Heidmann, “Expression of intracisternal A-particle retrotransposons in primary tumors of oncogene-expressing transgenic mice,” Oncogene, vol. 14, no. 24, pp. 2951–2958, 1997.
- G. Simmons, S. A. Glynn, J. A. Holmberg et al., “The Blood Xenotropic Murine Leukemia Virus-Related Virus Scientific Research Working Group: mission, progress, and plans,” Transfusion, vol. 51, no. 3, pp. 643–653, 2011.
- R. S. Arnold, N. V. Makarova, A. O. Osunkoya et al., “XMRV infection in patients with prostate cancer: novel serologic assay and correlation with PCR and FISH,” Urology, vol. 75, no. 4, pp. 755–761, 2010.
- S. Sabunciyan, N. Mandelberg, C. S. Rabkin, R. Yolken, and R. Viscidi, “No difference in antibody titers against xenotropic MLV related virus in prostate cancer cases and cancer-free controls,” Molecular and Cellular Probes, vol. 25, no. 2-3, pp. 134–136, 2011.
- H. C. T. Groom, V. C. Boucherit, K. Makinson et al., “Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome,” Retrovirology, vol. 7, no. 1, article 10, 2010.
- N. Onlamoon, J. Das Gupta, P. Sharma et al., “Infection, viral dissemination and antibody responses of rhesus macaques exposed to the human gammaretrovirus XMRV,” The Journal of Virology, vol. 85, no. 9, pp. 4547–4557, 2011.
- X. Qiu, P. Swanson, K. C. Luk et al., “Characterization of antibodies elicited by XMRV infection and development of immunoassays useful for epidemiologic studies,” Retrovirology, vol. 7, no. 1, article 68, 2010.
- R. K. Bagni, K. Beam, A. Meade, et al., “Development and optimization of a multiplex serological assay to detect XMRV antibodies,” in Proceedings of the 1st International Workshop on XMRV, abstract O_14, 2010.
- O. Hohn, H. Krause, P. Barbarotto et al., “Lack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients,” Retrovirology, vol. 6, no. 1, article 92, 2009.
- W. M. Switzer, H. Jia, O. Hohn et al., “Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States,” Retrovirology, vol. 7, no. 1, article 57, 2010.
- B. C. Satterfield, R. A. Garcia, H. Jia, et al., “Serological and PCR testing of persons with chronic fatigue syndrome in the United States shows no association with xenotropic or polytropic murine leukemia virus-related viruses,” Retrovirology, vol. 8, no. 1, article 12, 2011.
- O. Hohn, K. Strohschein, A. U. Brandt et al., “No evidence for XMRV in German CFS and MS patients with fatigue despite the ability of the virus to infect human blood cells in vitro,” PLoS One, vol. 5, no. 12, article e15632, 2010.
- A. L. Aloia, K. S. Sfanos, W. B. Isaacs et al., “XMRV: a new virus in prostate cancer?” Cancer Research, vol. 70, no. 24, pp. 10028–10033, 2010.
- E. Barnes, P. Flanagan, A. Brown et al., “Failure to detect xenotropic murine leukemia virus-related virus in blood of individuals at high risk of blood-borne viral infections,” Journal of Infectious Diseases, vol. 202, no. 10, pp. 1482–1485, 2010.