Review Article

Phylogeny-Directed Search for Murine Leukemia Virus-Like Retroviruses in Vertebrate Genomes and in Patients Suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Prostate Cancer

Figure 2

Structure and genome of a gammaretrovirus. The nucleocapsid is built from a hexameric lattice [46]. MA: matrix (p15), CA: capsid (p30), NC: nucleocapsid (p10), PR: protease, RT: reverse transcriptase (shown as a green dot), RH: RNAse H, IN: integrase, SU: surface unit (gp70), and TM: transmembrane protein (p15E). P12 is a small protein encoded from the portion between p15 and p30 in gag. LTR: long terminal repeat. The translation of glycoGag and normal Gag is indicated by the respective ribosome symbols. A Gag-Pol polyprotein is occasionally produced by suppression of a stop codon at the end of gag.
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