Review Article

XMRV Discovery and Prostate Cancer-Related Research

Figure 2

XMRV structure and morphology. (a) Structure of xenotropic murine leukemia virus-related virus showing viral core proteins from the gag gene (matrix (MA), capsid (CA), (IN), and nucleocapsid (NC) and p12); from pol (protease (PR), reverse transcriptase (RT), and integrase (IN)) and the envelope proteins (surface subunit (SU) and transmembrane subunit (TM) from env). Viral particles contain a lipid bilayer envelope and two RNA genomes. (b) Transmission electron microscope image of XMRV (courtesy of Dr. John Hackett, Jr., Abbott Diagnostics, Abbott Park, IL).
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(a)
432837.fig.002b
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