Review Article

MoMuLV-ts-1: A Unique Mouse Model of Retrovirus-Induced Lymphoma Transmitted by Breast Milk

Table 2

Percentages of changes in spleen, lymph node, and thymus due to MTCT of ts-1 virus by breastfeeding in control and infected pups.

GroupDescriptionSample size (n)SplenomegalyLymph node hypertrophyThymic hypertrophy

1Control pup nursed by infected surrogate mother9395.7%79.1%95.7%
2Infected pup nursed by infected surrogate mother9492.6%56.5%92.6%
3Infected pup nursed by control surrogate mother10846.3%25.9%46.3%
5Infected pup nursed by biological mother8889.8%61.4%89.8%
4 & 6Control—no infection1541.9%0.0%5.8%