Review Article
MoMuLV-ts-1: A Unique Mouse Model of Retrovirus-Induced Lymphoma Transmitted by Breast Milk
Table 2
Percentages of changes in spleen, lymph node, and thymus due to MTCT of ts-1 virus by breastfeeding in control and infected pups.
| Group | Description | Sample size (n) | Splenomegaly | Lymph node hypertrophy | Thymic hypertrophy |
| 1 | Control pup nursed by infected surrogate mother | 93 | 95.7% | 79.1% | 95.7% | 2 | Infected pup nursed by infected surrogate mother | 94 | 92.6% | 56.5% | 92.6% | 3 | Infected pup nursed by control surrogate mother | 108 | 46.3% | 25.9% | 46.3% | 5 | Infected pup nursed by biological mother | 88 | 89.8% | 61.4% | 89.8% | 4 & 6 | Control—no infection | 154 | 1.9% | 0.0% | 5.8% |
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