Endogenous Murine Leukemia Viruses: Relationship to XMRV and Related Sequences Detected in Human DNA Samples
Figure 2
Schematic cartoon of the hypothetical origin of X-MLV, P-MLV, and XMRV. The mice illustrate the inferred pattern of MLV-host evolution, starting with infection of mice with an exogenous XMLV, its endogenization, selection for the resistant (Xpr1n) receptor allele, and the subsequent evolution of the polytropic (P-MLV and MP-MLV) viruses capable of using the mutant receptor.
