Table 2: Virus-directed novel approaches.

Classes Comments Reference Targeting EBV episome Low dose hydroxyurea treatment Chodosh et al. [50], Slobod et al. [51] Inhibition of EBV transforming protein Antisense RNA against LMP-1 oncoprotein Kenney et al. [52] EBV-dependent expression of cellular toxins Expression of detrimental cellular proteins through OriP dependent expression vector Hirai et al. [53], Kenney et al. [54] Combination therapy Induction of EBV lytic replication + cytotoxic drugs Numerous, Listed in Table 3