Review Article
Advances in Virus-Directed Therapeutics against Epstein-Barr Virus-Associated Malignancies
Table 2
Virus-directed novel approaches.
| Classes | Comments | Reference |
| Targeting EBV episome | Low dose hydroxyurea treatment | Chodosh et al. [50], Slobod et al. [51] |
| Inhibition of EBV transforming protein | Antisense RNA against LMP-1 oncoprotein | Kenney et al. [52] | EBV-dependent expression of cellular toxins | Expression of detrimental cellular proteins through OriP dependent expression vector | Hirai et al. [53], Kenney et al. [54] |
| Combination therapy | Induction of EBV lytic replication + cytotoxic drugs | Numerous, Listed in Table 3 |
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