548657.fig.002a
(a)
548657.fig.002b
(b)
548657.fig.002c
(c)
548657.fig.002d
(d)
Figure 2: Purification of recombinant HIV-1 INs from B and CRF02_AG subtypes and comparison of their activities. (a) Purification products N1, N2, N3 and N4 of recombinant HIV-1 INs from B and CRF02_AG subtypes. (b)–(d) Comparison of DNA binding, 3′-processing and strand transfer activities, respectively, of the HIV-1 IN from B and CRF02_AG as a function of IN concentration.