The Possible Role of TLR2 in Chronic Hepatitis B Patients with Precore Mutation

Table 1

Clinical and pathological data of 51 chronic hepatitis B patients with and without precore mutation G1896A.

Clinical factor*	All subjects (𝑛=51)	Patients with wild-type variant (𝑛=22)	Patients with G1896A mutation (𝑛=29)	𝑃 value
Age (years)	37±10	36±9	38±11	0.4
logHBVDNA (copies/mL)	3.46±1.06	3.54±1.03	3.41±1.10	0.6
ALT (IU/L)	57±56	41±27	68±67	0.5
TLR2 (ng/mL)	4.2±2.7	3.4±2.2	4.8±2.9	0.03**
Histological activity index (HAI) score	4.8±2.3	4.2±1.7	5.3±2.6	0.076

∗Mean ± SD, **𝑃 value computed using the Mann-Whitney test.