Research Article
Mutations in the H, F, or M Proteins Can Facilitate Resistance of Measles Virus to Neutralizing Human Anti-MV Sera
Table 4
Transient neutralization study of the six escape mutants selected for further study.
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The standard Plaque Reduction Neutralization Test (PRNT50) was used to give a measure of the neutralizing capacities of anti-MV sera regarding the different mutants. The neutralizing capacity of four sera (sera 1, 2, 3, and 5) obtained from persons immunized against measles virus and one serum from a SSPE patient was studied for the different mutants relative to (non-mutated) Halle. The PRNT50 values obtained for each virus are indicated. |