Bioinorganic Chemistry and Applications
Volume 2009 (2009), Article ID 905320, 5 pages
doi:10.1155/2009/905320
Research Article
Synthesis and Characterization of bis[(2-ethyl-5-methyl-imidazo-4-yl)methyl]Sulfide and Its Coordination Behavior toward Cu(II) as a Possible Approach of a Copper Site Type I
1Laboratorio de Química Bioinorgánica, Departamento de Química, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, 36050, Guanajuato, GTO, Mexico
2Departamento de Química, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Unidad Cerro de la Venada S/N, 36040 Guanajuato, GTO, Mexico
3División de Estudios de Posgrado (DEP), Facultad de Ciencias Químicas, Universidad Autónoma de Nuevo León, Guerrero y Progreso S/N, Colonia Treviño, 64570, Monterrey, NL, Mexico
Received 9 February 2009; Accepted 12 May 2009
Academic Editor: Spyros Perlepes
Copyright © 2009 Juan D. Barrón-Garcés et al. This is an open access article distributed under the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The synthesis and characterization of a novel ligand, bis[(2-ethyl-5-methyl-imidazo-4-yl)methyl]sulfide (bemims), as well as a bemims-containing copper(II) coordination complex are described. In this complex, [Cu(bemims)X2] with X=NO3-, bemims acts as a tridentate ligand and two monodentate nitrate ions complete the coordination sphere. Both imidazole N atoms and the thioether S atom of bemims participate in coordination. The Cu(II) ion is five-coordinated with a slightly distorted square-pyramidal geometry (τ=.09). Electrochemical studies and spectroscopic data for this complex are compared with some blue copper proteins in order to assess its ability to mimic the copper center of type I copper proteins.