Synthesis and Evaluation of Novel Organogermanium Sesquioxides As Antitumor Agents

Table 2

Biodistribution of ^99mTc labeled compound 5 in nude mice bearing human colonic cancer xenografts at various time intervals (% ID/g, n = 3, 𝑥±SD).

Tissues	1 h	3 h	6 h	20 h
Stomach	10.10±3.89	5.57±0.89	1.27±0.25	0.59±0.18
Small intestine	1.29±0.58	1.06±0.11	3.09±3.27	0.33±0.14
Kidney	8.86±3.23	7.07±0.50	6.65±0.41	5.89±0.96
Liver	2.96±0.99	3.65±0.44	2.59±0.07	1.99±0.74
Lung	4.66±0.24	8.24±2.24	12.40±4.94	4.56±3.28
Muscle	0.72±0.84	0.49±0.34	0.44±0.34	0.11±0.04
Heart	0.64±0.23	0.58±0.09	0.34±0.00	0.21±0.05
Brain	0.07±0.02	0.11±0.06	0.07±0.01	0.03±0.01
Blood	1.26±0.28	0.97±0.18	0.55±0.06	0.21±0.06
Tumor	0.73±0.10	0.97±0.20	0.87±0.04	0.62±0.23