Synthesis and Evaluation of Novel Organogermanium Sesquioxides As Antitumor Agents

Table 3

T/NT of ^99mTc labeled compound 5 at various time intervals in nude mice bearing human colonic cancer xenografts (n = 3, 𝑥±SD).

Tissues	1 h	3 h	6 h	20 h
Stomach	0.07±0.02	0.18±0.06	0.69±0.10	1.02±0.07
Small intestine	0.63±0.20	0.92±0.15	0.62±0.64	1.93±0.47
Kidney	0.09±0.04	0.14±0.02	0.13±0.02	0.10±0.02
Liver	0.26±0.06	0.27±0.08	0.34±0.03	0.31±0.02
Lung	0.16±0.02	0.12±0.01	0.04±0.01	0.27±0.28
Muscle	1.01±1.18	3.88±4.19	2.77±2.05	5.81±0.93
Heart	1.22±0.34	1.66±0.19	2.54±0.15	3.00±1.05
Brain	10.70±3.34	9.99±4.53	12.90±2.95	18.30±5.72
Blood	0.72±0.23	1.18±0.02	1.60±0.26	3.01±0.98