Organotin Compound Derived from 3-Hydroxy-2-formylpyridine Semicarbazone: Synthesis, Crystal Structure, and Antiproliferative Activity

Table 4

The antiproliferative activity in vitro of H₂HyFoSc and its organotin complex 2 (expressed as ID₅₀ (𝜇M)) against MCF-7, T-24, A-549, and L-929 cancer cell lines.

Compounds	L-929	A-549	T-24	MCF-7
[H2HyFoSc] (𝟏)	n.a	175.0	n.a.	164.0
[Ph2(HyFoSc)Sn] (𝟐)	1.19	0.086	n.a.	8.65
[Ph2SnO]	10.73	47.10	n.a	3.46
Cisplatin	0.69	1.53	41.7	8.00