Effect of Common Buffers and Heterocyclic Ligands on the Binding of Cu(II) at the Multimetal Binding Site in Human Serum Albumin

<table>Titrations of HSA in the presence of 1.75 mol equivalents of Cu(II) with War (A) and Ibu (B) from 0 to 2.5 mol equivalents in 0.25 mol equivalent steps. The titration of War was terminated at 2 mol equivalents due to the loss of solution transparency. The solid lines represent linear fits to the data.</table>

Bioinorganic Chemistry and Applications

fig7

Figure 7

Figure 7: Effect of Common Buffers and Heterocyclic Ligands on the Binding of Cu(II) at the Multimetal Binding Site in Human Serum Albumin 