Synthetic Peptides as Structural Maquettes of Angiotensin-I Converting Enzyme Catalytic Sites

Figure 4

Circular dichroism spectra (left) and corresponding diagrams (right) of helical content through data analysis by CDNN software of (a) 2,2,2-trifluoroethanol (TFE) range from 0% to 100% of Zn²⁺-ACE_N(37) samples, at pH=5.0, 𝑇=25^∘C, 50 mM Tris-HCl, and 200 mM NaCl and (b) of pH range from 2.6 to 7 of Zn²⁺-ACE_N(37) samples, at 65% TFE, 𝑇=25^∘C, 50 mM Tris-HCl, and 200 mM NaCl.

(a)

(b)