Selectivity of Inhibition of N-Succinyl-l,l-Diaminopimelic Acid Desuccinylase in Bacteria: The product of dapE-gene Is Not the Target of l-Captopril Antimicrobial Activity
Figure 2
DapE independent inhibition of Salmonella enterica by L-captopril. (a) The knockout-strain has plasmid encoded dapE gene, and the medium is also supplemented with mDAP; (b) the knockout-strain has plasmid encoding dapE gene but no mDAP supplemented in the medium; (c) the knockout-strain has no plasmid encoding dapE gene but the medium was supplemented with mDAP; (d) the knockout-strain has no plasmid encoding dapE gene and no mDAP was supplemented.
