Thermodynamic Investigation and Mixed Ligand Complex Formation of 1,4-Bis-(3-aminopropyl)-piperazine and Biorelevant Ligands
Table 6
Stability constants of the ternary species in the ZnII-BAPP-amino acid, amide, or DNA constituent systems and proton-association constants and their binary stability constants.
OH−
BAPP
1 0 0-1
−7.96 (0.01)
—
1 0 0-2
−15.64 (0.01)
—
0 1 0 1
—
10.25 (0.01)
0 1 0 2
—
20.12 (0.02)
0 1 0 3
—
27.11 (0.03)
0 1 0 4
—
30.26 (0.01)
1 1 0 0
—
4.64 (0.03)
Alanine
Threonine
Serine
0 0 1 1
9.69 (0.01)
9.06 (0.01)
9.14 (0.01)
0 0 1 2
11.88 (0.02)
11.03 (0.02)
11.40 (0.01)
1 0 1 0
4.58 (0.03)
4.63 (0.09)
4.60 (0.09)
1 0 2 0
8.71 (0.06)
8.62 (0.08)
8.45 (0.08)
1 1 1 0
14.91 (0.01)
14.36 (0.08)
16.86 (0.08)
Ornithine
Glutamic acid
Histamine·2HCl
0 0 1 1
10.58 (0.00)
9.58 (0.01)
9.85 (0.01)
0 0 1 2
19.43 (0.02)
13.73 (0.01)
15.97 (0.01)
0 0 1 3
21.39 (0.02)
—
—
1 0 1 0
3.75 (0.09)
4.12 (0.09)
5.22 (0.02)
1 0 2 0
6.44 (0.05)
7.65 (0.05)
10.18 (0.05)
1 1 1 0
17.71 (0.06)
15.68 (0.10)
12.39 (0.10)
1 1 1 1
24.81 (0.06)
23.21 (0.10)
21.63 (0.07)
Glycinamide
Glutamine
0 0 1 1
7.60 (0.01)
8.95 (0.01)
1 0 1 0
3.28 (0.07)
4.12 (0.06)
1 1 1 0
12.47 (0.06)
15.41 (0.08)
Inosine
Thymine
Thymidine
0 0 1 1
8.55 (0.02)
9.58 (0.02)
9.50 (0.01)
1 0 1 0
3.52 (0.10)
4.82 (0.08)
4.47 (0.08)
1 1 1 0
14.15 (0.10)
15.89 (0.10)
15.72 (0.09)
1 1 1 1
20.38 (0.10)
and are stoichiometric coefficients corresponding to ZnII, BAPP, other ligand, and H+, respectively.
bStandard deviations are given in parentheses sum of square of residuals are less than 5E-7.
