Research Article

Synthesis and In Vitro Antitumor Activity of Two Mixed-Ligand Oxovanadium(IV) Complexes of Schiff Base and Phenanthroline

Table 3

The cell cycle analysis of the BEL-7402 cells induced by complexes 1 and 2 for 48 h.

Concentration (μM)The relative proportion of different phase
in the cell cycle (%)
G0/G1SG2/M

Control71.65 ± 1.8114.28 ± 0.3712.34 ± 1.78
3081.05 ± 0.23**7.94 ± 0.81**9.11 ± 0.57*
16081.78 ± 0.42**8.54 ± 0.40**8.66 ± 1.03*
12081.96 ± 1.88**8.18 ± 0.97**8.58 ± 0.60*

3085.46 ± 2.58**5.53 ± 0.23**7.74 ± 1.82*
26086.03 ± 1.23**5.33 ± 0.20**7.53 ± 1.21*
12086.00 ± 0.99**5.25 ± 0.51**7.89 ± 0.63*

Data are the mean ± SD of at least three independent experiments. < 0.05; < 0.01. < 0.05 versus the control, the difference was significant. < 0.01 versus the control, the difference was markedly significant.