Synthesis, Characterization, and Antibacterial Studies of Pd(II) and Pt(II) Complexes of Some Diaminopyrimidine Derivatives

Table 2

Zone of inhibition exhibited by metal complexes at 40 mg/mL (mm).

Complexes	E. coli	P. aeruginosa	S. aureus	S. faecalis	B. cereus	B. pumilus	K. pneumonia	P. vulgaris
[Pd(tmp)2Cl2]	30.0	NI	29.0	NI	32.0	NI	26.0	32.0
[Pd(tmp)2(NCS)2]	28.0	NI	NI	27.0	NI	NI	NI	28.0
[Pt(tmp)2Cl2]	32.0	NI	32.0	NI	34.0	NI	30.0	28.0
[Pt(tmp)2(NCS)2]	30.0	NI	25.0	NI	32.0	NI	NI	30.0
[Pd(pyrm)2Cl2]	NI	30	12	NI	NI	21	14	NI
[Pd(pyrm)2(NCS)2]	NI	33	29	NI	NI	20	33	NI
[Pt(pyrm)2Cl2]	14	NI	20	26	NI	NI	NI	NI
[Pt(pyrm)2(NCS)2]	20	NI	18	NI	28	NI	NI	30
Pyrimethamine	11	NA	13	12	10	NA	15	12
Trimethoprim	15.0	NA	12.0	18.0	17.0	NA	20.0	16.0

NI: no inhibition; NA: not applicable.